豆瓣菜中啶酰菌胺残留及膳食摄入风险评估

Assessment of boscalid residue and dietary intake risk in watercress

为评价啶酰菌胺在豆瓣菜生产上应用的安全性,采用QuEChERS方法进行样品前处理,液相色谱-串联质谱(LC-MS/MS)进行定量分析,检测了豆瓣菜中啶酰菌胺的最终残留量,对2种膳食食谱下的长期摄入风险进行了比较分析。结果表明,在添加水平范围内,在豆瓣菜空白样品中添加啶酰菌胺的平均回收率为89%~100%,相对标准偏差为5%~12%。GAP条件下,最终残留量为0.16~37.1 mg/kg。普通人群啶酰菌胺的国家估计每日摄入量(NEDI)为1.2151 mg/(kg bw),风险商为48.2%,表明其对一般人群健康产生的风险是可接受的,同时,使用WHO提供的单独每种农产品膳食量进行计算,啶酰菌胺每日摄入量为0.0830 mg/(kg bw),风险商为3.3%。经过对比分析,推荐使用WHO提供的膳食食谱数据进行长期膳食风险评估。

To evaluate the safety of boscalid in watercress,the samples were pretreated using QuEChERS method and quantitatively analyzed by liquid chromatography-tandem mass spectrometry(LC-MS/MS).The final residues in watercress were detected,and a comparative analysis of long-term intake risk using two different diets was conducted.The results showed that the average recoveries of boscalid in watercress was 89%-100%,with the relative standard deviation(RSD)of 5%-12%.Under the GAP conditions,the final residue was between 0.16-37.1 mg/kg.National estimates daily intake(NEDI)of boscalid was 1.2151 mg/(kg bw).Therefore,risk quotient(RQ)was 48.2%,which indicated that potential health risk caused by boscalid was not significant.If the individual dietary intake of each agricultural product provided by WHO was considered,the daily intake of boscalid was 0.0830 mg/(kg bw),which lead to the RQ of 3.3%.Using comparative analysis,it is recommended to use diet data provided by WHO for long-term dietary risk assessment.