体检人群胃溃疡患病危险因素的多元回归分析

Multiple regression analysis based on the risk factors of gastric ulcer in the physical examination population

目的探讨健康体检中心参加胃镜检查人群胃溃疡患病率和相关风险因素。方法采用横断面研究方法,收集2016年8月~2017年8月在陆军军医大学第一附属医院健康体检中心进行胃镜检查的研究人群,在胃镜检查前,通过面对面问卷调查方式收集流行病学相关信息,此外对研究对象进行常规体格检查和生化指标检测。胃溃疡患病相关风险因素研究采用多元逻辑回归方法进行分析。结果共计101人纳入该研究,其中男性59例,女性42例,平均年龄(46.67±8.22)岁。经胃镜诊断胃溃疡24人,患病率23.8%,男女性别比较差异无统计学意义(χ~2=0.88,P=0.35)。logistic回归分析结果显示高甘油三酯和饮酒是胃溃疡患病的风险因素,而其他因素与胃溃疡患病无关。结论较高的甘油三酯水平和饮酒是胃溃疡患病的风险因素,未来应进一步控制有胃溃疡风险人群的健康管理,对有经常饮酒和甘油三酯水平较高的人群进行健康干预,降低胃溃疡的患病风险。

Objective To explore the prevalence and risk factors of gastric ulcer among the people who took part in gastroscopy in the health examination center.Methods A cross-sectional study was conducted to collect the medical examination results from August 2016 to August 2017 in the physical examination center of Southwest Hospital,Army Medical University.Epidemiological information was collected through face-to-face questionnaires.In addition,routine physical examinations and biochemical indexes were performed on the subjects.The risk factors of gastric ulcer were analyzed by multiple logistic regression.Results A t 101 participants were included in the present study.59 were males and 42 were females.The mean age was 46.67±8.22 years.24 patients were diagnosed with gastric ulcer by gastroscopy,with a prevalence of 23.8%.There was no significant difference between male and female(2=0.88,P=0.35).Logistic regression showed that high triglycerides and alcohol consumption were risk factors for gastric ulcer,while other factors were not significantly associated with gastric ulcer.Conclusion The prevalence of gastric ulcer was relatively high in subjects participated in the gastroscope examination.Higher triglyceride levels and alcohol consumption are risk factors for gastric ulcer disease.In the future,health intervention should be carried out for people with frequent drinking and higher triglyceride levels to reduce the risk of gastric ulcer disease.