糖化血红蛋白对妊娠期糖尿病母婴结局的预测价值分析

Analysis of the predictive value of glycosylated hemoglobin for maternal and infant outcomes of gestational diabetes mellitus

目的分析糖化血红蛋白对妊娠期糖尿病母婴结局的预测价值。方法选取我院收治的妊娠期糖尿病孕妇60例作为研究对象,选取时间为2017年4月~2018年10月,根据孕妇的糖化血红蛋白水平将孕妇分为两组,即达标组(30例)、未达标组(30例),对两组孕妇进行持续的跟踪,观察两组孕妇的分娩方式、新生儿不良结局、孕妇并发症发生率、孕妇产后恢复情况。结果达标组孕妇的阴道自然分娩率高于未达标组,差异有统计学意义(P<0.05);达标组孕妇的阴道助产率、剖宫产率低于未达标组,差异有统计学意义(P<0.05);达标组孕妇新生儿不良结局发生率低于未达标组,差异有统计学意义(P<0.05);达标组孕妇的并发症发生率低于未达标组,差异有统计学意义(P<0.05);达标组孕妇的子宫恢复时间为(9.51±0.76)d、恶露消失时间为(13.26±1.25)d,明显短于未达标组孕妇的子宫恢复时间和恶露消失时间,差异有统计学意义(P<0.05)。结论糖化血红蛋白水平与妊娠期糖尿病孕妇的母婴结局有密切关联,因此要合理控制妊娠期孕妇的糖化血红蛋白水平,减少不良妊娠结局的出现。

Objective To analyze the predictive value of glycosylated hemoglobin for maternal and infant outcomes of gestational diabetes mellitus.Methods 60 pregnant women with gestational diabetes mellitus admitted to our hospital from April 2017 to October 2018 were selected as research subjects.According to their glycosylated hemoglobin level,the pregnant women were divided into two groups,respectively the standard group(n=30)and the non standard group(n=30).Continuous follow-up was carried out on the two groups of pregnant women to observe the mode of delivery,adverse neonatal outcomes,incidence of complications and postpartum recovery of pregnant women in the two groups.Results The vaginal natural delivery rate of pregnant women in the standard group was higher than that in the non-standard group,and the difference was statistically significant(P<0.05).The vaginal assistant labor rate and Cesarean section rate of pregnant women in the standard group were lower than those in the non-standard group,and the difference was statistically significant(P<0.05).The incidence of adverse neonatal outcomes of pregnant women in the standard group was lower than that in the non-standard group,and the difference was statistically significant(P<0.05).The incidence of complications of pregnant women in the standard group was lower than that in the non-standard group,and the difference was statistically significant(P<0.05).The recovery time of uterus and the disappearance time of lochia in the standard group were(9.51±0.76)d and(13.26±1.25)d respectively,which were significantly shorter than those in the non-standard group(P<0.05).Conclusion Glycosylated hemoglobin level is closely related to maternal and infant outcomes of pregnant women with gestational diabetes mellitus.Therefore,the glycosylated hemoglobin level of pregnant women should be reasonably controlled to reduce the occurrence of adverse pregnancy outcomes.