老年浅表性膀胱癌采用吡柔比星热灌注与常规灌注的临床对比分析

Clinical comparative analysis of pirarubicin thermal perfusion and conventional perfusion in the treatment of elderly superficial bladder cancer

目的:对比老年浅表性膀胱癌患者吡柔比星热灌注与常规灌注的临床效果。方法:2016年2月-2017年8月收治老年浅表膀胱癌患者72例,随机分为两组,各36例。对比组采用常规灌注方法治疗;观察组采用吡柔比星热灌注方法治疗。比较两组治疗效果。结果:观察组随访12个月和24个月复发率及不良反应发生率均低于对比组,治疗总满意率高于对比组,差异有统计学意义(P<0.05)。结论:采用吡柔比星热灌注方法治疗老年浅表性膀胱癌,效果更佳。

Objective:To compare the clinical effect of pirarubicin thermal perfusion and conventional perfusion in the treatment of elderly superficial bladder cancer.Methods:Methods:From February 2016 to August 2017,72 elderly patients with superficial bladder cancer were selected and randomly divided into two groups of 36 cases in each.The control group was treated with conventional perfusion.The observation group was treated with pirarubicin thermal perfusion.We compared the efficacy of the two groups.Results:In the observation group,followed up for 12 and 24 months,the recurrence rate and adverse reactions were lower than those in the control group,and the total satisfaction rate was higher than that in the control group,the difference was statistically significant(P<0.05).Conclusion:The clinical effect of pirarubicin thermal perfusion in the treatment of elderly superficial bladder cancer is better.