小儿急性喉炎治疗中雾化吸入肾上腺素的应用观察

Observation on the application of aerosol epinephrine inhalation in the treatment of acute laryngitis in children

目的分析小儿急性喉炎治疗中雾化吸入肾上腺素的应用效果。方法选取2019-01至2020-01山东省阳谷县人民医院收治的急性喉炎患儿110例为研究对象,采用随机抽选方式分为对照组(n=54)和观察组(n=56)。两组均进行基础治疗,在基础治疗上,对照组采用地塞米松注射液进行治疗,观察组采用雾化吸入肾上腺素+地塞米松进行治疗,比较两组症状改善时间、治疗效果及不良反应。结果观察组喘鸣、咳嗽、声音嘶哑、呼吸困难改善时间均短于对照组,差异具有统计学意义(P<0.05);观察组治疗总有效率高于对照组,差异具有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论小儿急性喉炎治疗中雾化吸入肾上腺素的应用效果显著,快速改善患儿临床症状,提升治疗效果,且不良反应无增加。

Objective To analyze the effect of aerosol inhaled epinephrine in the treatment of acute laryngitis in children.Methods From January 2019 to January 2020,110 patients with acute laryngitis treated in our hospital were selected as the study object.The patients were randomly divided into control group(n=54)and observation group(n=56).The two groups were treated with basic treatment.On the basis of basic treatment,the control group was treated with dexamethasone injection,and the observation group was treated with aerosol inhalation of epinephrine+dexamethasone.Results The improvement time of wheezing,coughing,hoarseness and dyspnea in the observation group was shorter than that in the control group,and the difference was statistically significant(P<0.05);the total effective rate in the observation group were higher than that in the control group,and the difference was statistically significant(P<0.022);the total incidence of adverse reactions was not statistically different between the observation group and the control group(P>0.05).Conclusions In the treatment of acute laryngitis in children,the effect of aerosol inhalation of epinephrine is remarkable,the clinical symptoms of children are improved quickly,the therapeutic effect is improved,and the incidence of adverse reactions is not increased.