睾丸精母细胞肿瘤2例的临床病理分析及文献复习

Clinicopathological analysis and literature review of 2 cases of spermatocytic seminoma

回顾性分析2例精母细胞肿瘤(spermatocytic tumour,ST)病理学特征及免疫组织化学检查结果,并进行随访。2例患者均为男性,年龄分别为39岁和61岁,均为无意发现睾丸肿块,行手术睾丸切除。组织学可见特征性3种细胞形态混合性生长,均未见肉瘤样变,术后随访情况良好。ST预后较好,具有独特临床病理特征,确诊主要依赖病理学形态和免疫表型相结合,出现肉瘤样变预后较差,应避免同精原细胞瘤混淆。

The pathological features and immunohistochemical examination of 2 cases of spermatocyte tumors were retrospectively analyzed and followed up. Two male patients were 39 and 61 years old, respectively. All of them had unintentionally found testicular mass and underwent surgical orchiectomy. Histologically, "tripartite"morphology was observed, and no sarcomatoid changes were discovered. Postoperative follow-up was good.Spermatocytic tumours have good prognosis and unique clinicopathological features. The diagnosis depends mainly on the combination of pathological morphology and immunohistochemistry. The prognosis of sarcomatoid transformation is poor, the confusion of seminoma should be avoided.