幼儿肺炎支原体肺炎MP-DNA载量与临床特征关系探讨

Relationships between MP-DNA load and clinical features in infants aged 1-3 years with Mycoplasma pneumoniae pneumonia

目的:探讨幼儿肺炎支原体肺炎(MPP)中MP-DNA载量与临床特征之间的关系。方法:收集40例2017年10月至2019年3月在我院儿科住院并诊断为MPP的1~3岁幼儿的临床资料,回顾性分析MP-DNA载量与临床特征之间的关系。结果:MP-DNA载量与幼儿MPP血清LDH水平、肺部X线/CT表现程度均呈正相关(P<0.01),与CRP、WBC、PLT均有一定相关性。结论:幼儿MPP病例中MP-DNA载量越高可能导致肺部影像表现越严重;MP-DNA载量与血清中LDH水平呈正相关,提示MP-DNA载量可能与疾病严重程度存在正相关。

Objective:To study the relationships between MP-DNA load and clinical features in infants with Mycoplasma pneumoniae pneumonia(MPP).Methods:From October 2017 to March 2019,the clinical data of 40 infants aged 1-3 years who were hospitalized in Pediatrics Department of our hospital and diagnosed as MPP were collected.The relationships between MP-DNA load and clinical features were analyzed.Results:MP-DNA load was positively correlated with serum LDH level and X/CT manifestations in MPP infants;to some extent it was correlated with CRP,WBC and PLT.Conclusion:The higher the MP-DNA load was,the more severe the pulmonary imaging was.MP-DNA load is positively correlated with serum LDH level,suggesting that MP-DNA load may be positively correlated with disease severity.