注射Na^99Tc^mO4后不同时间SPECT显像测量甲状腺体积的差异性研究

Difference of thyroid volume measured by single photon emission computed tomography imaging at different times after Na^99Tc^mO4 injection

目的探讨注射Na^99Tc^mO4后不同时间单光子发射计算机断层成像术(SPECT)显像测量甲状腺体积的差异。方法随机抽取2017年1月至2018年12月太原市中心医院收治的甲状腺功能亢进症患者132例,均行注射Na^99Tc^mO4后SPECT显像,分析断层积分法与平面法不同时间甲状腺显像情况。结果不同时间断层积分法与平面法测量甲状腺体积比较,差异未见统计学意义(t=1.889、1.968、1.928、1.720、1.712、1.511、1.893、1.802,P>0.05)。断层积分法、平面法20 min甲状腺显像与其他时间甲状腺显像呈正相关(P<0.05)。断层积分法显像评分为(3.40±1.57)分,高于平面法的(2.01±0.61)分,P<0.05;断层积分法体积CV值为低于平面法(t=19.245,P<0.05)。结论注射Na99TcmO4后不同时间SPECT显像测量甲状腺体积的差异较小,且甲状腺患者在注射试剂后1 h内均可进行SPECT显像。

Objective To investigate the difference of thyroid volume measured by single photon emission computed tomography (SPECT) imaging at different times after Na^99Tc^mO4 injection.Methods A total of 132 patients with hyperthyroidism admitted to Taiyuan Central Hospital from January 2017 to December 2018 were randomly selected. All patients underwent SPECT imaging after Na^99Tc^mO4 injection. The thyroid imaging at different time points was analyzed by tomosynthesis method and plane method.Results There were no statistically significant differences in the thyroid volume between the fault integration method and the planar method at different time points (t=1.889, 1.968, 1.928, 1.720, 1.712, 1.511, 1.893, 1.802;P>0.05). Thyroid imaging at different time intervals was positively correlated with 20-minute tomosynthesis method and plane method (P<0.05). The tomographic imaging score was 3.40 ±1.57, which was higher than that of the plane method (2.01 ± 0.61), P<0.05;and the volumetric CV value of the tomographic integral method was lower than the planar method (t=19.245, P<0.05).Conclusion The difference of thyroid volume measured by SPECT imaging at different time intervals after Na^99Tc^mO4 injection is small, and hyperthyroidism patients can perform SPECT imaging within 1 hour after injection of reagent.