新生儿暴发性肠道病毒感染的现状和防控策略

Current situation of nosocomial enterovirus infection in newborn infants and its prevention and control strategies

肠道病毒是引起新生儿病毒感染的常见病原,主要通过粪-口或呼吸道途径感染,可引起婴儿室或新生儿病房内的暴发流行。大部分患儿无症状或症状轻微,少数患儿病情严重,可并发脑炎、心肌炎、出血-坏死性肝炎等,重症患儿病死率明显增加。尽早识别、尽早隔离是防止肠道病毒院内暴发感染的重要措施。

Enterovirus is a common cause of neonatal virus infection,which is primarily transmitted by fecal-oral and respiratory routes and can cause nosocomial infection and outbreak in nursery or neonatal intensive care unit.Most infants with enterovirus infection are asymptomatic or just have mild self-limiting symptoms.Severe infection is less common but with significantly increased mortality,and may be complicated by the encephalitis/meningoencephalitis,myocarditis and/or hepatitis.Early recognition and prompt isolation of infants with enterovirus infection are important strategies for nosocomial infection control.