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京津冀血站实验室ALT检测不合格情况分析 被引量:4

Analysis on the positive ALT detection in labs of Beijing-Tianjin-Hebei blood stations
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摘要 目的了解京津冀区域血站实验室ALT检测情况,寻找各实验室间结果差异的原因,推进京津冀地区实验室同质化的建设。方法采用填写调查表的方式采集2018年京津冀区域各血筛实验室ALT检测情况信息,包括检测总数、阳性标本数等进行统计分析。结果京津冀地区血筛实验室间ALT检测策略有较大差异。使用的ALT检测设备有所不同,并且有53.33%的实验室没有备用ALT检测设备。设备使用年限也不尽相同,各实验室对ALT设备的更新和淘汰情况差别明显,因此不同仪器间ALT试剂间阳性率为7.29—51.32(P<0.05);不同厂家ALT试剂间阳性率为12.26—87.30(P<0.05);全部标本阳性率为7.29—97.62(P<0.05)、血小板血标本阳性率为0.00—63.26(P<0.05)、全血标本ALT阳性率为9.4—111.57(P<0.05)在实验室相互之间的比较差别明显。结论各实验室在ALT检测结果阳性率方面差异显著,导致的因素很多,对这些可能的问题进行针对性解决,探索出在区域内实现统一的从血液采集开始到实验室检测完成的标准化流程,使检测结果得到区域内各实验室认可,为进一步分析各实验室血液检测质量和实现京津冀采供血机构实验室结果同质化打下基础。 Objective To analyze the results of ALT detection of 15 blood bank laboratories(labs)from Beijing-Tianjin-Hebei region,understand the overall situation of ALT detection and further compare the differences existing among labs,so as to promote the construction of lab homogenization in Beijing-Tianjin-Hebei region.Methods By filling out the questionnaire,we collected the information of ALT detection of 15 blood bank labs from Beijing-Tianjin-Hebei region in 2018,including the total number of tests,the number of positive samples and so on for statistical analysis.Results Blood bank labs in Beijing-Tianjin-Hebei region differed on the ALT detection strategy.detection equipment,service life of equipment,as well as the update and phase-out of equipment,even 53.33%of the labs were lack in extras.There were significant differences in the positive rate of ALT reagents yielding among different equipment(7.29-51.32,P<0.05).In addition,there were significant differences in the positive rate of ALT reagents yielding among different manufacturers(12.26-87.30,P<0.05).The overall positive rate of ALT in all samples,platelet samples and whole blood samples were 7.29-97.62,0.00-63.26 and 9.4-111.57,respectively(P<0.05).Conclusion Varied factors contribute to the differences in the positive rates of ALT test among blood bank labs in Beijing-Tianjin-Hebei region.A standard procedure covering the collecting to testing for Beijing-Tianjin-Hebei labs should be considered so the test results can be accepted across this region,which can lay a foundation for further monitoring of blood test quality and homogenization of laboratory results in Beijing-Tianjin-Hebei region.
作者 徐云鹏 葛红卫 王瑞 潘彤 韩卫 王鹏 杨莉 孙绍秋 曹晓 崔立晔 魏超 于桂军 房金娟 刘彩侠 王学刚 甄志军 刘晓杰 杜文功 王露楠 张晓飞 XU Yunpeng;GE Hongwei;WANG Rui;PAN tong;HAN wei;WANG Peng;YANG li;SUN Shaoqiu;CAO Xiao;CUI liye;WEI Chao;YU Guijun;FANG jinjuan;LIU Caixia;WANG Xuegang;ZHEN Zhijun;LIU Xiaojie;DU Wengong;WANG Lunan;ZHANG Xiaofei(Zhangjiakou Blood Bank,Zhangjiakou 075000,China;Beijing Red Cross Blood Center;Tianjin Blood Center;Hebei Blood Center;Tongzhou Blood Bank;Tanggu Blood Bank;Tangshan Blood Bank;Baoding Blood Bank;Cangzhou Blood Bank;Hengshui Blood Bank;Chengde Blood Bank;Handan Blood Bank;Xingtai Blood Bank;Qinhuangdao Blood Bank;Langfang Blood Bank;National Center for Clinical Laboratories)
出处 《中国输血杂志》 CAS 2020年第4期311-315,共5页 Chinese Journal of Blood Transfusion
关键词 丙氨酸氨基转移酶 血筛实验室 京津冀地区 ALT blood bank lab Beijing-Tianjin-Hebei region
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