非神经系统恶性肿瘤患者围术期缺血性脑卒中的研究进展

Research Progress of Perioperative Ischemic Stroke in Patients with Non-nervous System Malignant Tumor

非神经系统恶性肿瘤患者围术期缺血性脑卒中死亡率高,其病因和发病机制复杂。由于恶性肿瘤患者围术期高凝状态、麻醉、血流动力学改变等因素,缺血性脑卒中成为最常见、最严重的并发症之一,特别是老年患者。而且由于麻醉效应阻碍了临床医生对脑卒中症状的识别,常导致诊断和治疗的延迟,进而导致不良结果。本文主要综述了非神经系统恶性肿瘤患者围术期缺血性脑卒中流行病学、病理生理机制、危险因素方面的研究进展,为临床工作中预防和及时诊治该病提供依据。

The mortality rate of ischemic stroke is high in patients with non-nervous system malignant tumor during perioperative period,and its etiology and pathogenesis are very complicated.Due to the perioperative hypercoagulability,anesthesia,hemodynamic changes and other factors in patients with malignant tumors,ischemic stroke has become one of the most common and serious complication,especially in elderly patients.Moreover,the anesthetic effect hinders clinicians'recognition of stroke symptoms,the diagnosis and treatment are often delayed,leading to adverse results.Therefore,this paper mainly reviews the research progress in epidemiology,pathophysiology and risk factors of perioperative ischemic stroke in patients with non-nervous system malignant tumor,which is helpful for prevention and timely diagnosis and treatment in clinical work.