肿瘤免疫治疗及其相关标记物的研究现状与思考

Present status and thought on tumor immunotherapy and related biomarkers

肿瘤免疫治疗作为新的治疗手段,改变了肿瘤的治疗模式,逐步发展成为继手术、化疗、放疗之后的第四种肿瘤治疗模式。但是免疫治疗应答率有限,寻找精准的肿瘤免疫治疗生物标志物作为靶标或检测及评价指标有助于摆脱此困境,探索更加有效的免疫治疗模式可以使患者获益更多,同时应注意预防及应对免疫相关不良反应。随着研究的不断深入,免疫治疗将为肿瘤患者带来更多的曙光。

Tumor immunotherapy has changed mode for tumor treatment and has gradually developed into the fourth tumor treatment option after surgery,chemotherapy,and radiotherapy.However,the response rate of immunotherapy is limited.Identification of accurate tumor immunotherapy biomarkers as targets or detection and evaluation indicators would be helpful to improve the response rate.Explorations of more effective delivery of immunotherapy would benefit more patients.Prevention and response to immune-related adverse reactions are also necessary.With the development of research,immunotherapy will bring more hope to cancer patients.