胺碘酮治疗快速性心律失常的临床疗效及药学分析

Clinical Efficacy and Pharmaceutical Analysis of Amiodarone in the Treatment of Tachyarrhythmia

目的探讨胺碘酮治疗快速性心律失常的临床疗效及药学原理。方法将我院2017年1月至2019年1月的70例快速性心律失常患者,两组均给予常规抗心律失常药物治疗,随机分组,常规抗心律失常药物治疗组单纯进行常规用药,胺碘酮辅助治疗组对于患者开展给予常规抗心律失常药物治疗联合胺碘酮辅助治疗。比较效果。结果胺碘酮辅助治疗组疗效、心功能和生活质量等各项指标优于常规抗心律失常药物治疗组,P<0.05。胺碘酮辅助治疗组心律失常转窦性心律的时间、心室率恢复正常的时间、症状改善的时间短于常规抗心律失常药物治疗组,P<0.05。两组治疗期间无严重不良反应发生。结论快速性心律失常患者实施给予常规抗心律失常药物治疗联合胺碘酮辅助治疗效果确切。

Objective To explore the clinical effect and pharmaceutical principle of amiodarone in the treatment of tachyarrhythmia.Methods 70 patients with tachyarrhythmia from January 2017 to January 2019 in our hospital were randomly divided into two groups.The conventional antiarrhythmic drug treatment group was treated with conventional drug only,and the amiodarone assisted treatment group was treated with conventional antiarrhythmic drug combined with amiodarone assisted treatment.Compare results.Results The therapeutic effect,cardiac function and quality of life of amiodarone assisted therapy group were better than those of conventional antiarrhythmic drugs treatment group(P<0.05).The time of arrhythmia to sinus rhythm,the time of ventricular rate returning to normal and the time of symptom improvement in amiodarone assisted group were shorter than those in conventional antiarrhythmic drug treatment group(P<0.05).No serious adverse reactions occurred in the two groups.Conclusion The effect of routine antiarrhythmic drugs combined with amiodarone is definite.