胆舒软胶囊治疗胆囊结石伴疼痛的临床效果评价

Clinical Evaluation of Danshu Soft Capsule in the Treatment of Gallstone Complicated with Pain

目的评价胆舒软胶囊对胆囊结石伴发疼痛的治疗效果。方法 A试验选取2018年12月至2019年11月为期一年的门诊慢性结石性胆囊炎伴右上腹隐痛患者共74例,35例观察组口服胆舒软胶囊,39例对照组口服消炎利胆片;B试验选取同期急诊入院治疗的胆囊结石伴急性胆绞痛患者共101例,53例观察组口服胆舒软胶囊,48例对照组口服消炎利胆片。以服药后疼痛变化为观察指标,计算治疗有效率,利用统计学方法分别对两个试验数据进行分析。结果 A试验中观察组有效率80.0%,对照组有效率76.9%,经统计学分析无差异;B试验中观察组有效率78.0%,对照组有效率59.1%,具有统计学意义(P <0.05)。结论胆舒软胶囊和消炎利胆片对慢性结石性胆囊炎伴上腹隐痛的治疗都具有较好的效果,且二者效果相当;胆舒软胶囊对急性胆绞痛治疗的有效率和缓解疼痛的速度可能优于消炎利胆片。

Objective To evaluate the therapeutic effect of Danshu Soft Capsule on gallstone accompanied by pain.Methods The trial A selected 74 outpatients with chronic calculous cholecystitis accompanied by right upper abdominal cryptodynia from December 2018 to November 2019.35 cases in the observation group took Danshu Soft Capsule orally and 39 cases in the control group took XiaoyanLidan Tablets orally.In the B trial,101 cases of gallstones accompanied by acute biliary colic were selected for emergency admission treatment in the same period as trial A,53 cases in the observation group,takingDanshu Soft Capsule,48 cases of control group took XiaoyanLidan Tablet orally.Taking the pain changes after taking medicine as the observation index,the effective rate of treatment was calculated,and the data of the two experiments were analyzed by statistical method.Results In experiment A,the effective rate of the observation group was 80.0%,while that of the control group was 76.9%.There was no statistical difference between the two groups.In experiment B,the effective rate of the observation group was 78.0%,and that of the control group was 59.1%,with statistical significance(P<0.05).Conclusion Anshu Soft Capsule and XiaoyanLidan Tablet have good effect in the treatment of chronic calculous cholecystitis with epigastric cryptodynia,and both of them have the same effect;Danshu Soft Capsule may be superior to XiaoyanLidan Tablet in the effective rate and the speed of relieving pain for the treatment of Acute biliary colic.