活体供肺肺叶移植手术技术的研究进展

Advances in research on surgical techniques of living donor lobar lung transplantation

肺移植已成为治疗终末期肺病唯一有效的手段。活体供肺肺叶移植成功扩大了供器官池,缓解了供肺短缺问题。为应对供受者移植物体积不匹配、血管变异等情况,相关手术技术被不断拓展,这些技术对于公民逝世后器官捐献供肺肺叶移植也具有重大借鉴意义。从伦理角度考虑,活体供肺肺叶移植仅限用于疾病进展快速、难以等待供肺的危重患者。在供肺持续短缺的情况下,活体供肺肺叶移植相关技术将得以继续发展。

Lung transplantation has become the only effective treatment for end-stage lung diseases. Living donor lobar lung transplantation has successfully expanded the donor pool and eased the shortage of donor lungs. In order to deal with size mismatch and vascular variability, related surgical techniques have been continuously expanded, and these techniques also have significant reference significance for lobar lung transplantation from donation after citizen′s death. From an ethical point of view, living donor lobar lung transplantation should be limited to critically ill patients with rapid disease progression and difficulty in waiting for donor lungs from donation after citizen′s death. In the case of continued shortage of donor lungs, living donor lobar lung transplantation related techniques will continue to develop.