原发性乳腺淋巴瘤的超声征象与病理特征分析

Analysis of ultrasonic signs and pathological features in primary breast lymphoma

目的探讨原发性乳腺淋巴瘤(PBL)的超声征象与病理特点并分析其相关性。方法回顾性分析2016年1月至2019年3月该院收治的15例PBL患者,术前均行常规超声检查,术后病理均证实为PBL,分析其超声征象与病理特点的关系。结果15例患者中单侧发病13例,双侧发病2例。共检出病灶21个,病灶最大径线小于或等于20 mm 7个,20~50 mm 12个,>50 mm 2个。超声征象以低回声为主,内有丝网状分隔,且可见较丰富的血流信号(12个)。病理以弥漫性大B细胞淋巴瘤为主(12例),不同分型的淋巴瘤超声表现基于病理组织学的差异,常与淋巴瘤细胞浸润程度、范围及病程不同时期相关。结论PBL超声征象表现各异,与病理基础密切相关,充分认识二者的关系,综合多个超声特点能够获得较准确的诊断。

Objective To explore the ultrasonic signs and pathological features in primary breast lymphoma(PBL),and analyse the correlation between them.Methods A retrospective analysis of 15 cases of patients with PBL admitted to the hospital from January 2016 to March 2019 was performed.All patients received routine ultrasound examination before operation,and were finally confirmed as PBL by postoperative pathology.The relationship between ultrasound signs and pathological features was analyzed.Results Of the 15 patients,there were 13 cases of unilateral tumor and 2 cases of bilateral tumor.A total of 21 lesions were detected,including 7 lesions with the longest diameters≤20 mm,12 lesions with the longest diameters 20—50 mm and 2 lesions with the longest diameters>50 mm.The ultrasound signs were mainly hypoechoic with filamentous separation and abundant blood flow signal(12 lesions).The pathology results showed that most cases(12 cases)were diffuse large B-cell lymphoma.The sonographic appearances of the different classifications of lymphoma were based on pathological histological types,which was often related to the degree,range and different stages in lymphoma cell infiltration.Conclusion The manifestations of PBL ultrasound signs are varied and closely related to the pathological basis.A more accurate diagnosis can be obtained by fully understanding the reationship between them and integrating multiple ultrasonic characteristics.