阿奇霉素治疗肺炎支原体感染所致小儿过敏性咳嗽的疗效观察

Effect of azithromycin on allergic cough in children caused by Mycoplasma pneumoniae infection

目的观察使用阿奇霉素治疗肺炎支原体所致小儿过敏性咳嗽的临床疗效。方法选取2018年10月~2019年10月期间接受治疗的肺炎支原体所致过敏性咳嗽患儿104例,按照随机数字法分为对照组和试验组,每组各52例。给予对照组患儿常规治疗,试验组患儿在此基础上给予加用阿奇霉素进行治疗。对比两组患儿的临床疗效。结果试验组患儿的治疗有效率为92.31%,对照组患儿的治疗有效率为73.08%,差异具有统计学意义(P<0.05);治疗后,试验组患儿的FVC、MMF、PEF水平分别为(2.06±0.43)L、(1.64±0.53)L、(3.13±0.73)L/min,对照组患儿的差异FVC、MMF、PEF水平分别为(1.83±0.34)L、(1.48±0.61)L、(2.88±0.74)L/min,差异有统计学意义(P<0.05)。结论给予肺炎支原体所致的过敏性咳嗽患儿行阿奇霉素治疗,可显著改善患儿肺功能,提高临床疗效。

Objective To observe the clinical effect of azithromycin in the treatment of allergic cough in children caused by Mycoplasma pneumoniae.Methods from October 2018 to October 2019,104 children with allergic cough caused by Mycoplasma pneumoniae who were treated in our hospital were divided into control group and experimental group according to the random number method,52 cases in each group.On this basis,the children in the experimental group were treated with azithromycin.The clinical effects of the two groups were compared.Results The effective rate of treatment was 92.31%in the experimental group and 73.08%in the control group,the difference was statistically significant(P<0.05);after treatment,the levels of FVC,MMF and PEF in the experimental group were(2.06±0.43)L,(1.64±0.53)L,(3.13±0.73)L/min,respectively,and the levels of FVC,MMF and PEF in the control group were(1.83±0.34)L,(1.48L,respectively±0.61)L,(2.88±0.74)L/min,with statistical significance(P<0.05).Conclusion Azithromycin can significantly improve the lung function and clinical effect of children with allergic cough caused by Mycoplasma pneumoniae,.