布地奈德混悬液联合特布他林用于小儿哮喘的治疗的效果分析

Therapeutic analysis of budesonide suspension combined with terbutaline in children with asthma

目的探讨布地奈德混悬液联合特布他林用于小儿哮喘治疗的效果。方法选取2018年2月至2019年2月住院哮喘患儿共88例,随机分为两组,每组44例。两组患儿均给予常规基础治疗;对照组给予布地奈德混悬液雾化治疗;研究组给予布地奈德混悬液联合特布他林雾化治疗。比较两组患儿临床疗效、临床症状改善情况、肺功能改善情况及炎性因子水平变化情况。结果研究组总有效率高于对照组(P<0.05);研究组治疗后哮鸣音、喘息、咳嗽评分均低于对照组(P<0.05);研究组治疗后,PEF、PEV1均高于对照组(P<0.05);研究组治疗后,CRP水平、白细胞介素-6水平均低于对照组(P<0.05)。结论小儿哮喘治疗应用布地奈德混悬液联合特布他林,对患儿治疗、哮喘症状控制效果更好,肺功能改善更明显,能有效减少炎性因子对机体的损害,值得推广应用。

Objective To explore the effect of budesonide suspension combined with terbutaline in the treatment of children asthma.Methods Eighty-eight children with asthma were enrolled in the study from February 20 to February 2019,which were randomly divided into two groups,44 in each group.Both groups were given routine basic treatment;the control group was given budesonide suspension atomization;the study group was given budesonide suspension combined with terbutaline atomization.The clinical efficacy,improvement of clinical symptoms,improvement of pulmonary function and changes of inflammatory factors were compared between the two groups.Results The total effective rate of the study group was higher than that of the control group(P<0.05);the wheezing,shortness of breath,and cough scores of the study group were lower than those of the control group(P<0.05);after treatment,the PEF and PEV1 of the study group were higher than the control group group(P<0.05),the CRP level and interleukin-6 level in the study group were lower than those in the control group(P<0.05).Conclusion The application of budesonide suspension combined with terbutaline in the treatment of asthma in children has better effect on children′s treatment and asthma symptom control,makes more obvious improvement of lung function,and can effectively reduce the harm of inflammatory factors to the body,which is worth popularizing.