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硫酸镁联合钙通道阻断剂对中重度妊娠期高血压患者血管内皮功能指标及自然分娩率的影响 被引量:7

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摘要 妊娠期高血压(gestational hypertension,GH)为常见妊娠并发症,据统计,我国GH发病率为9.4%~10.4%,孕妇或围生期胎儿死亡率高达7%~12%[1]。现阶段,临床治疗GH以解痉、降压为主,硫酸镁、钙通道阻断剂硝苯地平均为常用药物,二者联合治疗效果已经临床证实。现阶段,GH发病机制尚无统一概述,研究指出,其发生、发展与血管内皮功能损伤存在重大关系[2]。血管内皮细胞钙黏蛋白(VE-cadherin)为内皮细胞特异性钙黏蛋白,与其功能稳定密切相关。
作者 郝翠红
出处 《中国药物与临床》 CAS 2020年第13期2209-2211,共3页 Chinese Remedies & Clinics
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