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重型新型冠状病毒肺炎的发病机制与血液净化治疗的应用 被引量:2

Pathogenesis of severe corona virus disease 2019 and application of blood purification therapy
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摘要 2019年出现新型冠状病毒肺炎(简称新冠肺炎)疫情。人群对新型冠状病毒(2019-nCoV)普遍易感,目前还没有特效治疗药物,对重型、危重型患者的有效救治是降低新冠肺炎病死率的关键。重型新冠肺炎患者的病情会急剧恶化而出现多器官功能衰竭(MOF),其机制可能是由“炎症风暴”引起。血液净化治疗能清除炎症因子,阻断“炎症风暴”,从而减轻炎症反应对机体的损伤,对重型、危重型新冠肺炎患者的救治有重要价值。 In December 2019,corona virus disease 2019(COVID-19)occurred.People are generally susceptible with 2019 novel coronavirus(2019-nCoV),as a result,the effective treatment of severe and critical cases is the key to reduce the fatality rate of this disease.Severe cases of COVID-19 will develop a sharp deterioration of multiple organ failure(MOF),which is caused by"inflammatory storm".Blood purification treatment can remove inflammatory factors,block"cytokine storm",and result in reducing the inflammatory response to the injury of the body.This technique has great value to the treatment of severe and critical COVID-19 patients.
作者 裴茂华 王瑶 陈倩 龚作炯 Pei Maohua;Wang Yao;Chen Qian;Gong Zuojiong(Department of Infectious Disease,Renmin Hospital of Wuhan University,Wuhan 430060,Hubei,China)
出处 《中国中西医结合急救杂志》 CAS CSCD 北大核心 2020年第4期499-501,共3页 Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
关键词 新型冠状病毒肺炎 发病机制 血管紧张素转化酶2 炎症风暴 血液净化治疗 Corona virus disease 2019 Pathogenesis Angiotensin converting enzyme 2 Inflammatory storm Blood purification therapy
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