回顾性分析20例卵巢腺鳞癌的临床病理特征及预后

The clinicopathological features and prognosis of 20 cases of ovarian adenosquamous carcinoma were analyzed retrospectively

目的回顾性分析卵巢腺鳞癌的临床病理特征及预后情况,以提高认识和诊治水平。方法检索PubMed、中国知网等数据库资料,系统地回顾所有相关的文献,共收集国内外正式发表的19篇有关卵巢腺鳞癌的报道共20例患者。结果卵巢腺鳞癌临床表现缺乏特异性,术前诊断困难。病理起源多样化,病理学上可合并其他病理类型,需仔细鉴别。研究显示,影响预后的因素包括年龄、病理类型、临床分期及治疗方案等,药物靶向治疗、细胞免疫治疗等生物治疗方法可为罕见病理类型提供新思路。结论卵巢腺鳞癌的预后极差,病理类型、临床分期仍是影响预后的关键因素。由于卵巢腺鳞癌罕见报道,需要收集更多患者进行研究分析,以探讨有效的治疗方案,改善患者的预后。

Objective The clinicopathological features and prognosis of ovarian adenosquamous carcinoma were retrospectively analyzed to improve the level of diagnosis and treatment. Methods Searched Pub Med, CNKI and other databases, systematically reviewed the relevant literature, a total of19 articles were published at home and abroad about 20 cases of ovarian adenosquamous carcinoma. Results Ovarian adenosquamous carcinoma lacks specificity in clinical manifestations, mainly for the lower abdomen mass, ascites, pelvic pain and so on. Pathological diversity, due to difficult preoperative diagnosis, pathology need to carefully identify. Studies have confirmed that the factors affecting the prognosis of the tumor, including age, pathological type, clinical stage and treatment programs. Targeted therapy, immunotherapy and other biological treatment methods provide new ideas for rare pathological types. Conclusion The prognosis of ovarian adenosquamous carcinoma is very poor, pathological type, clinical stage is the key factor affecting prognosis.Due to rare reports of ovarian adenosquamous carcinoma, more patients need to be collected for research and analysis to explore effective treatment options and improve the prognosis of such patients.