新型冠状病毒肺炎和炎症性肠病的相关性研究

Association between COVID-19 and inflammatory bowel disease

新型冠状病毒肺炎(COVID-19)是2019年12月份爆发的传染病,以喉咙痛、发烧、咳嗽、呼吸困难、咳痰等呼吸道症状为主。传染速度快,传染性强,主要经飞沫传播、接触传播,后经证明粪口传播也可作为一种传播途径。消化道症状为部分COVID-19患者的首发症状,在诊断方面对于消化科医师来说是一个巨大的挑战。炎症性肠病(inflammatory bowel disease, IBD)是一种慢性自身免疫性炎性疾病,可能与COVID-19在发病机制上存在相关性,因此疫情期间IBD患者的管理十分重要。我们根据已经发表的病例及文献报道对IBD和COVID-19之间的关系进行阶段性总结。

COVID-19 is an infectious disease broken out in Dec. 2019. The respiratory tract symptoms are main symptoms, such as sore throat, fever, cough, dyspnea and expectoration. The COVID-19 can be spreaded by droplet, direct contaction and fecal-oral afterwards. The intestinal symptoms are primary in a part of COVID-19 patients. The COVID-19 is a huge challenge for gastroenterologists, especially for inflammatory bowel disease(IBD). IBD is a chronic autoimmune inflammatory disease. The management for IBD patients is crucial to decrease the susceptibility of COVID-19. Mechanically, there may be association between IBD and COVID-19 in some degree. We summarized the association between IBD and COVID-19 by reviewing the cases and literatures about IBD and COVID-19 periodically.