复合微孔多聚糖止血粉在消化内镜治疗中的应用

Application of compound microporous polysaccharide hemostatic powder in the treatment of digestive endoscopy

目的探讨复合微孔多聚糖止血粉在消化内镜治疗中应用的安全性及疗效。方法 70例行消化内镜治疗患者(结直肠息肉黏膜切除术、胃黏膜下剥离术、结直肠黏膜下剥离术)术中联合使用复合微孔多聚糖止血粉止血(止血粉组),对比同期未联合使用止血粉的84例消化内镜治疗患者(对照组),比较2组消化内镜治疗术中出血和术后发生迟发性出血的风险。结果止血粉组术中止血成功率100%,无1例发生术后迟发性出血。对照组术中止血成功78例,术中止血成功率93%,术后迟发性出血4例,发生率为5%,总止血成功率88%,术中止血成功率和总止血成功率均低于止血粉组(P均<0.05)。结论联合使用复合微孔多聚糖止血粉在消化内镜治疗中能加强止血效果,提高止血成功率,值得推广。

Objective To explore the safety and efficacy of compound microporous polysaccharide hemostatic powder in the treatment of digestive endoscopy.Methods Seventy patients received endoscopic treatment including colorectal polyps endoscopic mucosal resection,gastric endoscopic submucosal dissection and colorectal endoscopic submucosal dissection in combination with compound microporous polysaccharide hemostatic powder(hemostatic powder group),and 84 cases were treated with endoscopic interventions alone(control group).The risk of intraoperative hemorrhage and delayed postoperative hemorrhage was statistically compared between two groups.Results The success rate of intraoperative hemostasis was 100%(70/70)and no delayed postoperative hemorrhage occurred in the hemostatic powder group.In the control group,the success rate of intraoperative hemostasis was 93%(78/84).The incidence rate of delayed postoperative hemorrhage was 5%(4/84).The total hemostasis rate was 88%,the success rate of intraoperative hemostasis and the total hemostasis rate significantly lower than that in the hemostatic powder group(both P <0.05).Conclusion The combined use of compound microporous polysaccharide hemostasis powder can improve hemostasis in the treatment of digestive endoscopy,which is worthy of clinical application.