牵正散加减治疗特发性面神经麻痹风寒外袭型患者的临床疗效观察

Observation of clinical effect of Qiangzhengsan on patients with idiopathic facial paralysis caused by wind cold

目的观察牵正散加减治疗特发性面神经麻痹患者风寒外袭型的临床疗效。方法选取2016年6月—2019年11月收治的特发性面神经麻痹风寒外袭型患者80例,按照随机数字表法分成对照组(40例)和观察组(40例)。对照组口服泼尼松联合甲钴胺注射液治疗,观察组在对照组基础上采用牵正散加减治疗。观察两组患者的临床疗效,H-B面神经功能分级,面部残疾指数[躯体功能(FDIP)、社会生活功能(FDIS)]评分及不良反应发生情况。结果观察组与对照组患者治疗后总有效率分别为92.50%、72.50%,差异有统计学意义(P<0.05)。两组患者治疗前H-B面神经功能分级及FDIP、FDIS评分对比,差异无统计学意义(P>0.05)。两组患者治疗后H-B面神经功能分级、FDIP评分均高于治疗前(P<0.05),FDIS评分均低于治疗前(P<0.05),且观察组改善程度均优于对照组,差异有统计学意义(P<0.05)。两组患者治疗后不良反应发生率比较差异无统计学无意义(P>0.05)。结论牵正散加减治疗特发性面神经麻痹风寒外袭型的效果显著,可改善临床症状,促进患者快速康复。

Objective Observation of the clinical effect of Qianzhengsan on the treatment of wind-cold exogenous idiopathic facial paralysis.Methods A total of 80 patients with idiopathic facial paralysis of the cold type who were treated in our hospital from June 2016 to November 2019 were selected and randomly divided into a control group(40 cases)with oral prednisone combined with mecobalamin injection,and an observation group(40 cases)on the basis of the control group was treated with Zhengzhengsan addition and subtraction.Through the two groups of patients(HB)facial nerve function score,facial disability index(somatic functioning(FDIP),social life function(FDIS))score and side effects were compared evaluate Qianzheng powder to treating cold outside attack idiopathic facial paralysis the clinical effect.Results The total effective rate of the observation group and the control group was 92.50%and 72.50%,respectively(P<0.05).The HB,FDIP and FDIS scores of the observation group and the control group before treatment.There was no significant difference in the difference between the observation group and the control group(P>0.05).The HB scores of the observation group and the control group were higher than those before the treatment,and the difference between the observation group and the control group was statistically significant(P<0.05).The FDIP scores of the control group were higher than those before treatment,and the FDIS scores were lower than before treatment(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The effect of Qianzhengsan on the treatment of idiopathic facial paralysis of wind-phlegm obstruction is effective,which can improve clinical symptoms,reduce adverse reactions of patients,and promote rapid recovery of patients.