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干扰ROCK1基因对鼻咽癌的细胞侵袭影响分析

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摘要 目的:分析干扰ROCK1基因对鼻咽癌的细胞侵袭的影响。方法:选取2016年4月~2019年10月收治的鼻咽癌患者40例,采集鼻咽癌标本、癌旁组织各40份,以免疫组化法对ROCK1基因表达情况进行检测。结果:鼻咽癌组织ROCK1阳性率明显高于癌旁组织(P<0.05);经30μM浓度、10μM浓度药物干扰ROCK1处理后,标本ROCK1表达水平明显降低,癌细胞侵袭能力明显降低(P<0.05),且药物浓度越大,ROCK1表达水平、癌细胞侵袭能力越低。结论:干扰ROCK1基因可降低鼻咽癌的细胞侵袭能力,是鼻咽癌治疗的重要思路。
出处 《实用中西医结合临床》 2020年第8期119-120,共2页 Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
基金 广东省深圳市科技计划项目编号(编号:JCYJ20170307141944428)。
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