摘要
设计了一种具有三重功能的G-四链体发夹探针,结合氧化石墨烯对单双链DNA的不同淬灭性质,以NF-kB p50作为模型靶标,实现了对转录因子的快速、灵敏检测。
This paper designed a triple-functional G-quadruplex hairpin probe that combined with the different quenching properties of graphene oxide for single and double-stranded DNA and achieved rapid and sensitive detection of transcription factors using NF-k B p50 as model target.
作者
褚秀玲
Chu Xiuling(Shandong taian ecological environment monitoring center,Shandong taian 271000)
出处
《云南化工》
CAS
2020年第7期87-88,92,共3页
Yunnan Chemical Technology
关键词
G-四链体探针
氧化石墨烯
转录因子
灵敏检测
G-quadruplex probe
graphene oxide
transcription factors
sensitive detection
