自拟补中益气汤配合常规西医疗法对慢性阻塞性肺疾病急性加重期的疗效评价

Efficacy of the Buzhong Yiqi decoction plus conventional western medicine in acute exacerbation of chronic obstructive pulmonary disease

目的:探讨自拟补中益气汤配合常规西医疗法对慢性阻塞性肺疾病急性加重期的疗效。方法:按照治疗方案不同将100例慢性阻塞性肺疾病急性加重期患者分为观察组50例和对照组50例,对照组接受常规西医疗法治疗,观察组患者在此基础上接受自拟补中益气汤治疗,比较两组治疗效果。结果:观察组的治疗总有效率高于对照组,差异显著(P<0.05);观察组患者治疗后第1 s用力呼气量(Forced Expiratory Volume in 1s,FEV1)、用力肺活量(Forced Vital Capacity,FVC)、FEV1/FVC水平均高于对照组,差异显著(P<0.05);观察组患者治疗后日排痰量及中医证候积分均低于对照组,差异显著(P<0.05)。结论:自拟补中益气汤配合常规西医疗法对慢性阻塞性肺疾病急性加重期疗效显著,可明显改善患者临床症状和肺功能,值得临床推荐。

objective:To investigate the efficacy of self-made Buzhong Yiqi decoction(自拟补中益气汤)plus conventional western medicine on acute exacerbation of chronic obstructive pulmonary disease.Methods:According to different treatment regimens,100 cases with acute exacerbation of chronic obstructive pulmonary disease were divided into the observation group(50 cases)and control group(50 cases).The control group took conventional treatment.The observation took the Buzhong Yiqi decoction.Results:The total effective rate in the observation group was significantly higher than the control group(P﹤0.05).Forced expiratory FEV1,FVC and FEV1/FVC levels in the observation group at the 1 st day after treatment were all higher than those in the control group(P﹤0.05).The daily sputum discharge and the score of TCM symptoms in the observation group were significantly lower than the control group(P﹤0.05).Conclusion:The selfmade Buzhong Yiqi decoction plus conventional western medicine has a significant effect on the acute exacerbation of chronic obstructive pulmonary disease,and can significantly improve the clinical symptoms and lung function,which is worthy of clinical recommendation.