逐瘀降浊汤联合阿托伐他汀治疗脑梗塞的临床效果观察

Observation on treating cerebral infarction with the Zhuyu Jiangzhuo decoction plus atorvastatin

目的:探讨逐瘀降浊汤联合阿托伐他汀治疗脑梗塞的临床效果。方法:选择2017年1月-2019年1月期间在本院治疗的65例脑梗塞患者,随机分为对照组(32例)和观察组(33例)。两组患者均给予常规对症治疗,在此基础上,对照组采用阿托伐他汀治疗,观察组在对照组基础上逐瘀降浊汤治疗,对比两组患者治疗效果、神经功能缺损恢复效果、中医证候积分及血脂水平改善情况。结果:观察组患者西医疗效和中医疗效总有效率均显著高于对照组,差异具有统计学意义(P<0.05)。两组离院前、出院后3个月和出院后6个月美国国立卫生研究院卒中量表(National Institute of Health Stroke Scale,NIHSS)评分均显著低于入院时,差异具有统计学意义(P<0.05)。观察组离院前、出院后3个月、出院后6个月NIHSS评分显著低于对照组,差异具有统计学意义(P<0.05)。观察组治疗后中医证候积分主症和次症积分均显著低于对照组,差异均具有统计学意义(P<0.05);观察组治疗后中医证候积分总分显著低于对照组,差异均具有统计学意义(P<0.05)。结论:阿托伐他汀治疗脑梗塞基础上联合逐瘀降浊汤治疗可有效提升临床疗效,促进神经功能康复,同时有助于提高血脂调节效果,临床应用价值较高。

Objective:To investigate the clinical effect of the Zhuyu Jiangzhuo decoction(逐瘀降浊汤)plus atorvastatin on cerebral infarction.Methods:65 patients with cerebral infarction who were treated in our hospital from January to September 2019 were randomly divided into the control group(32 cases)and observation group(33 cases).The control group was treated with atorvastatin,and the observation group was treated with the Zhuyu Jiangzhuo decoction more.The treatment effect,the recovery effect of nerve function defect,TCM syndrome score and the improvement of blood lipid level were compared.Results:The total effective rotes of western medicine and TCM in the observation group were significantly higher than that in the control group(P<0.05).The NIHSS scores in the two groups before leaving hospital,3 months after leaving hospital and 6 months after leaving hospital were significantly lower than the two groups at the time of admission(P<0.05).those in the observation group were significantly lower than that in the control group points(P<0.05).After treatment,the scores of main symptoms and secondary symptoms in the observation group were significantly lower than those in the control group,and the differences were statistically significant(P<0.05),the total scores of TCM syndromes in the observation group were significantly lower than those in the control group points,and the differences were statistically significant(P<0.05).Conclusion:Atorvastatin with the Zhuyu Jiangzhuo decoction on cerebral infarction can effectively improve the clinical efficacy,promote the neurological rehabilitation of patients,and help to improve the blood lipid regulation effect,and the clinical application value is higher.