加味泻黄散治疗复发性口腔溃疡临床研究

Clinical study on Modified Xiehuang Powder in the treatment of recurrent oral ulcer

目的:研究加味泻黄散用于治疗复发性口腔溃疡的临床疗效。方法:择取2018年1月-2019年1月于日照市人民医院收治的58例复发性口腔溃疡患者作为研究对象,将其随机划分为试验组与对照组,对照组患者使用常规治疗方法,试验组患者则在常规疗法基础上加用加味泻黄散,比较两组患者临床疗效。结果:①临床治疗总有效率:试验组患者为93.10%(27/29),远高于对照组患者,组间差异存在统计学意义(P <0.05);②复发率:对两组患者进行为期6个月的追踪随访,发现试验组患者复发率为6.90%(2/29),低于对照组患者,组间差异存在统计学意义(P <0.05)。结论:加味泻黄散用于治疗复发性口腔溃疡疗效显著,值得在临床中进行大规模应用推广。

Objective: To study the clinical effect of Modified Xiehuang Powder(加味泻黄散) in the treatment of recurrent oral ulcer. Methods: A total of 58 patients with recurrent oral ulcer admitted to People’s Hospital of Rizhao from January 2018 to January 2019 were selected for this study. They were randomly divided into the experimental group and the general group. The general group received conventional treatment, while the experimental group received Modified Xiehuang Powder on the basis of conventional treatment. The clinical efficacy of the two groups was compared. Results: ① The total effective rate of clinical treatment of the patients in the experimental group was 93.10%(27/29), which was much higher than that of the general group, and the difference between groups was statistically significant(P<0.05). ② The recurrence rate of patients in the two groups were followed up for a period of six months, and it was found that the recurrence rate of patients in the experimental group was 6.90%(2/29), which was much lower than that in the general group, and the difference between groups was statistically significant(P<0.05). Conclusion: Modified Xiehuang Powder has a significant effect in the treatment of recurrent oral ulcer and is worthy of large-scale application and promotion in clinical practice.