左甲状腺素钠联合补硒治疗甲状腺功能减退的效果与安全性

Effect and safety of levothyroxine sodium combined with selenium supplementation in the treatment of hypothyroidism

目的:探讨左甲状腺素钠联合补硒治疗甲状腺功能减退的临床效果。方法:2017年12月-2019年3月收治甲状腺功能减退患者72例,随机分为两组。对照组给予左甲状腺素钠治疗;观察组给予左甲状腺素钠联合补硒治疗。比较两组治疗效果。结果:观察组临床总有效率高于对照组,差异有统计学意义(P<0.05);观察组治疗后血脂及甲状腺功能各项指标水平均优于对照组,差异有统计学意义(P<0.05)。结论:左甲状腺素钠联合补硒方法治疗甲状腺功能减退,效果显著,且安全性良好。

Objective:To investigate the clinical effect of levothyroxine sodium and selenium supplementation in the treatment of hypothyroidism.Methods:From December 2017 to March 2019,72 patients with hypothyroidism were enrolled,they were randomly divided into two groups.The control group was treated with levothyroxine sodium and the observation group was treated with levothyroxine sodium combined with selenium supplementation.The therapeutic effects between the two groups was compared.Results:The total effective rate in the observation group was higher than the control group,the difference was statistically significant(P<0.05).The various of indicator levels of blood lipids and thyroid function in observation group were better than control group after treatment,the differences were statistically significant(P<0.05).Conclusion:The treatment of hypothyroidism by levothyroxine sodium combined with selenium supplementation is effective and safe.