基于碲膜置换制备粗糙金电极的无酶葡萄糖电化学传感器

Non-Enzymatic Glucose Electrochemical Sensor Based on Rough Au Electrode Fabricated by Tellurium Film-Replacement

高粗糙度薄层贵金属纳米结构的界面组装对研制高性能的电化学传感器具有重要意义。以玻碳电极(GCE)上电沉积锯齿状形貌的半导体碲(Te)膜为模板,再将其与HAuCl4进行原电池置换反应,制备了条棒状的粗糙Au薄膜修饰电极(AuTe-R/GCE)。在碱性环境中采用循环伏安法研究了AuTe-R/GCE对葡萄糖的电催化氧化性能,并藉此构建了无酶葡萄糖电化学传感器。结果表明,与普通的镀金GCE(Aucon/GCE)和裸Au电极相比,AuTe-R/GCE对葡萄糖的电催化氧化活性更高;在最优条件下,采用恒电位计时安培法检测了葡萄糖浓度,AuTe-R/GCE对葡萄糖的线性检测范围(LDR)为0.01~2.00 mmol·L^-1,灵敏度为3.8 mA·mmol^-1·cm^-2,检测下限(LOD)为55 nmol·L^-1;且该无酶葡萄糖电化学传感器抗干扰能力强,稳定性好。以半导体碲膜制备特定形貌与高粗糙度薄层纳米Au的方法具有简便、快捷和低成本等优点,有望在高活性纳米电催化剂的界面组装及其电化学性能研究中被广泛应用。

The interfacial assembly of high roughness thin-layer noble metal nanostructures is important for the development of high performance electrochemical sensors.Herein,by electrodepositing a semiconductor Te film with sawtoothed shape on the glassy carbon electrode(GCE)as the template and a subsequent galvanic replacement reaction with HAuCl4,the bar-shaped and rough Au thin film modified glassy carbon electrode(AuTe-R/GCE)was fabricated.The electrocatalytic performance of the modified electrode toward glucose oxidation was studied in alkaline condition via cyclic voltammetry,and the glucose non-enzymatic amperometric sensor was constructed.Compared with the conventional gold-electroplated GCE(Aucon/GCE)and bare Au electrode,the AuTe-R/GCE showed the higher electrocatalytic activity toward the oxidation of glucose.Under the optimal conditions,the glucose concentration was detected via potentiostatic chronoamperometry,and the AuTe-R/GCE showed a linear detection range of glucose concentration from 0.01 to 2.00 mmol/L with a sensitivity of 3.8 mA·mmol^-1·cm-^2,and limit of detection(LOD)of 55 nmol·L^-1,with strong anti-interference ability and good stability,being superior to most of relevant reports.The new method for preparing the specific morphology and high roughness thin-layer nano-sized Au by replacement with semiconductor Te film presented here has the advantages of convenience,rapidness and low-cost,and is expected to be widely used in the interfacial assembly of highly active nanoelectrocatalysts and their electrochemical performances research.