连续性血液净化应用于ICU重症脓毒血症治疗临床疗效

Clinical Efficacy of Continuous Blood Purification in the Treatment of Severe Sepsis in ICU

目的 ICU重症脓毒血症患者通过连续性血液净化治疗,对患者得到的临床治疗效果以及安全性进行研究分析。方法从该院在2016年7月—2019年7月间收治的重症脓毒血症患者中随机抽取60例患者,根据随机分组的方法进行分组,分别分成观察组和对照组,对两组患者的治疗总有效率、治疗前后的平均动脉压、急性生理与慢性健康评分(APACHE-2)以及不同时间的病死率进行比较,评价连续性血液净化的治疗效果。结果观察组患者的治疗总有效率为93.3%,对照组患者的治疗总有效率为73.3%(χ^2=15.625,P<0.05);观察组患者的治疗后的平均动脉压和APACHE-2评分分别为:(62.03±5.36)mmHg,(12.36±1.16)分(t=5.365、5.850,P<0.05);观察组患者的治疗12个月后和24个月后的病死率低于对照组患者。结论 ICU重症脓毒血症患者,通过连续性血液净化治疗,治疗有效率显著提升,临床症状明显改善,病死率降低。

Objective To study and analyze the clinical treatment effect and safety of patients with severe sepsis in patients with severe sepsis through continuous blood purification treatment. Methods From July 2016 to July 2019, 60 patients with severe sepsis were randomly selected from the hospital, and they were divided into two groups according to the random grouping method. They were divided into observation group and control group. The total effective rate of treatment, average arterial pressure before and after treatment, acute physiological and chronic health scores(APACHE-2), and fatality rate at different times were compared in this group to evaluate the effect of continuous blood purification. Results The total effective rate of treatment in the observation group was 93.3%, and the total effective rate of treatment in the control group was 73.3% (χ^2=15.625,P <0.05);the average of the observation group after treatment was Arterial pressure and APACHE-2 scores were:(62.03±5.36)mmHg,(12.36±1.16)points(t=5.365,5.850,P<0.05);the fatality rate of patients in the observation group after 12 months and 24 months of treatment was lower than those in the control group. Conclusion In patients with severe sepsis in ICU, through continuous blood purification treatment, the treatment efficiency is significantly improved, the clinical symptoms are significantly improved, and the fatality rate is reduced.