奥美拉唑和法莫替丁治疗反流性食管炎疗效评价

Evaluation of the Efficacy of Omeprazole and Famotidine in the Treatment of Reflux Esophagitis

目的利用奥美拉唑和法莫替丁对反流性食管炎患者进行分别治疗,展开对照试验,对患者所获得的治疗效果进行严格比较。方法该院在2017年1月—2018年1月这一期间,收治了60例反流性食管炎的患者,随机分成两组,每组30例患者,比较两组患者的治疗总有效率,对比两组患者的临床症状的改善情况,评价联合用药的治疗效果。结果观察组患者的总有效率为93.3%(28/30),对照组患者的总有效率为70.0%(21/30),(χ^2=12.632,P<0.05),观察组患者临床症状得到的改善程度优良于对照组患者,组间差异有统计学意义(t=5.155、6.013、5.761、6.688,P<0.05)。结论反流性食管炎患者通过服用奥美拉唑展开医治,治疗效果优良,可以获得更加优良的预后效果。

Objective To treat patients with reflux esophagitis separately by using omeprazole and famotidine, and carry out a controlled trial to strictly compare the treatment effects obtained by patients. Methods During the period from January 2017 to January 2018, 60 patients with reflux esophagitis were admitted to the hospital and randomly divided into two groups, each with 30 patients. The two groups were compared. The total effective rate of treatment was compared with the improvement of clinical symptoms of the two groups of patients, and the effect of combined treatment was evaluated. Results The total effective rate of patients in the observation group was 93.3%(28/30), the total effective rate of patients in the control group was 70.0%(21/30) (χ^2=12.632,P <0.05). The clinical symptoms of the observation group were better than those of the control group. the data difference between the two groups was statistically significant(t =5.155, 6.013, 5.761, 6.688, P <0.05). Conclusion Patients with reflux esophagitis can be treated by taking omeprazole. The treatment effect is excellent, and a better prognosis can be obtained.