内镜黏膜下注射自体血定位在早期大肠癌腹腔镜手术中的临床价值

Clinical value of endoscopic submucosal injection of autologous blood during laparoscopic surgery for early colon cancer patients

目的分析内镜黏膜下自体血注射定位在早期大肠癌腹腔镜手术中的应用价值。方法将2016年1月至2019年9月在深圳市龙岗区第五人民医院行腹腔镜手术的早期大肠癌患者共40例为研究对象,根据数字表法随机分成对照组(术中肠镜定位)和观察组(术前注射自体血定位)各20例,观察两组的手术时长、术中出血量、住院时间以及术后排气时间。结果观察组的手术时长比对照组更短(P<0.05);两组术中出血量、排气及住院时间差异不显著(P>0.05)。两组均未出现腹痛、发热以及过敏反应等不适症状和手术并发症。结论术前在肠镜黏膜下行自体血注射定位能缩短早期大肠癌腹腔镜手术的手术时间,是定位病变一种简单、有效、安全、经济的方式,值得采用。

【Objective】 To analyze the applied value of endoscopic submucosal injection of autologous blood during laparoscopic surgery for early colon cancer patients. 【Methods】 A total of 40 early colon cancer patients underwent the laparoscopic surgery from January 2016 to September 2019 in our hospital were selected as research subjects. According to random number table, patients were assigned to two groups, 20 cases in each group. The control group received the positioning during surgery;the observation group received the autologous blood injection before surgery. The operation time, intraoperative blood loss,hospitalization time and postoperative exhaust time were compared.【Results】The operation time in the observation group was shorter than that in the control group(P<0.05);the intraoperative blood loss, exhaust time and hospitalization time between groups was not significantly different(P>0.05). Both of groups had no uncomfortable symptoms like stomachache, fever and anaphylaxis,as well as surgical complications. 【Conclusion】 Before surgery, the endoscopic submucosal injection of autologous blood can shorten the operation time. The simple, efficient, safe and economic method is worthy of clinical application.