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血浆D二聚体与纤维蛋白原检测对弥散性血管内凝血的诊断价值 被引量:4

Value of plasma D-Dimer and fibrinogen dectection in diagnosis for disseminated intravascular coagulation
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摘要 目的探讨血浆D二聚体(D-D)与纤维蛋白原(FIB)检测对弥散性血管内凝血(DIC)的诊断价值。方法选取2017年5月至2019年4月南阳市第一人民医院收治的38例DIC患者作为观察组,选取同期常规体检者38例作为对照组,比较两组血浆D-D、FIB水平,以《弥散性血管内凝血诊断中国专家共识(2017年版)》中DIC诊断标准为金标准,统计DIC检出率,比较D-D、FIB、D-D+FIB诊断DIC灵敏度、准确度、特异度、漏诊率、误诊率。结果观察组血浆D-D水平高于对照组,FIB水平低于对照组(P<0.05);D-D检出DIC 40例,非DIC 39例;FIB检出DIC 39例,非DIC37例;D-D+FIB检出DIC 38例,非DIC 38例;D-D+FIB诊断DIC灵敏度(100.00%)、准确度(100.00%)、特异度(100.00%)高于D-D (73.68%、71.05%、68.42%)和FIB (76.32%、75.00%、73.68%),漏诊率(0.00%)、误诊率(0.00%)低于D-D (26.32%、31.58%)和FIB (23.68%、26.32%)(P<0.05)。结论检测血浆D-D、FIB可用于DIC的诊断,D-D+FIB能提高诊断DIC灵敏度、准确度、特异度,减少漏诊与误诊。
作者 于晶晶 YU Jingjing
出处 《中国医学工程》 2020年第7期70-72,共3页 China Medical Engineering
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