功能磁共振成像熵连接工具箱的研制

Development of an entropy connectivity analyze toolbox for functional magnetic resonance imaging

目的:为了分析不同脑区间功能磁共振成像(fMRI)信号的效应连接状况,研制一个可计算时间序列间熵连接的工具箱。方法:在Windows环境下,MATLAB平台中编写熵连接代码,利用图形用户界面进行工具箱界面开发,通过设计控件的属性、编写回调函数及调用MATLAB内置程序计算熵连接。结果:该工具箱可实现时间序列间熵连接的计算,并可对结果进行统计分析。用户可输入已生成的脑区fMRI信号时间序列,也可以通过本工具箱生成感兴趣脑区的时间序列,进行计算熵连接。结论:该工具箱易于操作,界面友好,可极大地提高科研人员的效率。

Objective To develop a toolbox for calculating the entropy connectivity between time series,thereby analyzing the effective connectivity of functional magnetic resonance imaging signals from different brain regions.Methods UnderWindows environment,entropy connectivity codes were written in MATLAB platform,and graphical user interface was used for toolbox interface development.The entropy connectivity was calculated by designing the properties of controls,writing callback functions and calling MATLAB built-in programs.Results The developed toolbox realized the calculation of the entropy connectivity between time series and the statistical analysis on the calculated results.The entropy connectivity was calculated after the user input of the generated time series of functional magnetic resonance imaging signals from brain regions,or the time series of brain regions of interest which were generated by the toolbox.ConclusionWith a friendly interface,the toolbox is easy to operate and can greatly improve efficiency of researchers.