超声造影结合实时弹性成像技术评估乳腺癌患者血流动力学指标

Evaluation of hemodynamic indexes of breast cancer patients by contrast-enhanced ultrasound combined with real-time elastography

目的:探讨分析超声造影结合实时弹性成像技术对乳腺癌患者血流动力学指标的评估价值。方法:选择127例女性患者156个乳腺肿块,肿块均经病理证实,患者术前均经超声造影、实时弹性成像及彩色多普勒超声血流动力学检查。以病理检查结果作为标准,分析良恶性肿瘤患者超声造影、实时弹性成像及血流动力学相关指标差异。结果:超声造影显示良性肿块121个,恶性肿块35个。实时弹性成像显示良性肿块120个,恶性肿块36个。恶性肿块组收缩期峰值血流速度和阻力指数高于良性肿块组(P<0.05)。超声造影、实时弹性成像联合血流动力学诊断灵敏度和特异度高于超声造影、实时弹性成像和血流动力学单项诊断。结论:超声造影、实时弹性成像技术联合血流动力学诊断乳腺癌具有重要意义,可提高灵敏度和特异度。

Objective To explore the value of contrast-enhanced ultrasound combined with real-time elastography in evaluating hemodynamic indexes of breast cancer patients.Methods A total of 156 breast masses were selected from 127 female patients.All the masses were diagnosed pathologically.Before operation,the patients underwent contrast-enhanced ultrasound,real-time elastography,and hemodynamics examination by color Doppler ultrasound.Based on the results of pathological examination,the differences between begin masses and malignant masses in the related indexes among contrastenhanced ultrasound,real-time elastography and hemodynamics were analyzed.Results There were 121 benign and 35 malignant masses diagnosed by contrast-enhanced ultrasound,and 120 benign and 36 malignant masses diagnosed by realtime elastography.The resistance index and peak systolic velocity of malignant masses group were higher than those of benign masses group(P<0.05).The diagnostic sensitivity and specificity of the diagnosis by the combination of contrastenhanced ultrasound and real-time elastography plus hemodynamics were higher than those of the diagnosis by contrastenhanced ultrasound or real-time elastography or hemodynamics separately.Conclusion The combination of contrastenhanced ultrasound and real-time elastography plus hemodynamics which can improve sensitivity and specificity is of great significance in the diagnosis of breast cancer.