Lvis支架辅助弹簧圈血管内栓塞治疗颅内破裂动脉瘤的临床效果和安全性

Clinical effect and safety of Lvis stent-assisted endovascular coil embolization in treating ruptured intracranial aneurysm

目的:探讨Lvis支架辅助弹簧圈血管内栓塞治疗颅内破裂动脉瘤中的临床效果和安全性。方法:选取84例颅内破裂动脉瘤患者作为观察对象,随机分为A、B两组,每组42例患者。A组采用Lvis支架辅助弹簧圈血管内栓塞方式进行治疗,B组采用Solitaire支架辅助弹簧圈血管内栓塞方式进行治疗。采用RS评分、Raymond评分和GOS评分对临床效果进行评价,并对治疗后的不良反应发生率及复发率进行分析。结果:RS评分方面,A组为(0.23±0.57)分,B组为(2.48±0.96)分,A组低于B组(P<0.05);Raymond评分方面,A组Ⅰ级发生率为92.24%,B组为78.57%,A组高于B组(P<0.05);GOS评分方面,A组5分的发生率为92.86%,B组为73.81%,A组高于B组(P<0.05)。不良反应发生率方面,A组为2.38%,B组为21.43%,A组低于B组(P<0.05)。复发率方面,A组无一例复发,B组复发率为4.76%,A组低于B组(P<0.05)。结论:Lvis支架辅助弹簧圈血管内栓塞治疗颅内破裂动脉瘤,临床效果好且具有一定安全性。

Objective To investigate the clinical effect and safety of Lvis stent-assisted endovascular coil embolization for ruptured intracranial aneurysm.Methods A total of 84 patients with ruptured intracranial aneurysm were enrolled in the study and then randomly divided into group A and group B,with 42 patients in each group.Lvis stent-assisted endovascular coil embolization was used in group A,while Solitaire stent-assisted endovascular coil embolization was adopted in group B.Rankin scale(RS),Raymond scale and Glasgow outcome scale(GOS)were used to evaluate the clinical effect,and the incidence of adverse reactions and recurrence rate after treatment were also analyzed.Results The RS score in groupAwas lower than that in group B(0.23+0.57 vs 2.48+0.96,P<0.05).The analysis on Raymond score revealed that the incidence of gradeⅠaneurysm packing in group A was higher than that in group B(92.24%vs 78.57%,P<0.05);and the analysis on GOS score showed that the proportion of 5 points in group A was 92.86%,higher than 73.81%in group B(P<0.05).The incidence of adverse reactions in group A was lower than that in group B(2.38%vs 21.43%,P<0.05).There was no recurrence in group A,but the recurrence rate was 4.76%in group B(P<0.05).Conclusion In the treatment of patients with ruptured intracranial aneurysm,Lvis stent-assisted endovascular coil embolization has satisfactory clinical effects,with certain safety.