从中医及西医角度理解和对抗心包粘连

Understanding and Countering Pericardial Adhesions from the Perspective of Traditional Chinese Medicine and Western Medicine

一直以来,心包粘连都是心外科医生的噩梦,特别是在二次开胸手术中及术后对心功能的影响方面。在西医的角度看来,粘连的形成机制主要是由于组织的上皮或间皮层的破坏引发的,同时纤维蛋白溶解活性的下降和纤维蛋白沉积的增加所导致的;中医学认为,心包粘连的形成与气滞血瘀、瘀血内结、脉络闭阻,导致正气亏虚有关。因此,了解形成机制,以及它们的相互作用,对预防和对抗心包粘连的发展及开发出更多有效的治疗方法是至关重要的。西医中的机械屏障以及抗黏附剂,中医中活用活血化瘀药物及制剂常用于对抗粘连的形成。

Pericardiosymphysis has always been a nightmare for cardiac surgeons,especially in the aspect of the impact on cardiac function during and after secondary thoracotomy.From the perspective of the Western medicine,the formation mechanism of adhesion is mainly caused by the destruction of epithelium or mesothelial layer of tissue,the decrease of fibrinolytic activity and the increase of fibrin deposition.Traditional Chinese medicine believes that the formation of pericardiosymphysis is related to the stagnation of vital energy and the stasis of blood,blood stasis internal knot and venous occlusion,which leads to the deficiency of vital energy.Therefore,understanding the formation mechanisms and their interactions is essential to prevent and combat pericardiosymphysis and to develop more effective treatments.The mechanical barrier and anti-adhesives in Western medicine,drugs and preparations for activating blood circulation and removing blood stasis in Chinese medicine are often used to combat the formation of pericardiosymphysis.