摘要
开发了一种新型高效的钯催化的三氟硼酸钾盐与氧杂降冰片烯的不对称开环反应的方法.在温和的条件下,可得到相应的顺-2-芳基-1,2-二氢萘-1-醇产物,其产率良好,目标产物对映体选择性较高.
A new,versatile and highly efficient palladium-catalyzed asymmetric ring-opening reaction of oxabenzonorbornadienes with a wide range of potassium trifluoroborate salts was developed.The corresponding cis-2-aryl-1,2-dihydronaphthalen-1-ol products were obtained in good yields with moderate to good enantioselectivities under mild conditions.
作者
陶萍芳
黄俊
刘玉钊
韦光明
王艺菲
韦贤生
黄国保
李秀英
Tao Pingfang;Huang Jun;Liu Yuzhao;Wei Guangming;Wang Yifei;Wei Xiansheng;Huang Guobao;Li Xiuying(Guangxi Key Laboratory of Agricultural Resources Chemistry and Biotechnology,College of Chemistry and Food Science,Yulin Normal University,Yulin,Guangxi 537000;College of Chemistry and Materials,Nanning Normal University,Nanning 530001)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2020年第6期1630-1637,共8页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(Nos.21971204,216222203,21702161)
陕西省创新能力支撑计划(No.2020TD-022)
陕西省教育厅科学基金(No.19JS064)资助项目.
关键词
氧杂降冰片烯
三氟钾硼酸盐
不对称开环反应
oxabenzonorbornadiene
trifluoroborate salt
asymmetric ring-opening reaction
