针刺结合穴位埋线对周围性面瘫患者面部神经及免疫指标的影响

Effects of Acupuncture Combined with Acupoint Catgut Embedding on Facial Nerve and Immune Indexes in Patients with Peripheral Facial Paralysis

【目的】探讨针刺结合穴位埋线对周围性面瘫患者面部神经及免疫指标的影响。【方法】将106例周围性面瘫患者随机分为治疗组和对照组,每组各53例,对照组给予西药配合电针常规治疗,治疗组在对照组基础上结合穴位埋线治疗,连续治疗2个月。治疗2个月后,观察2组患者治疗前后面部残疾指数量表(FDI)、多伦多(Sunnybrook)面神经系统评分、生存质量量表(WHOQOL-BREF)评分以及免疫球蛋白A(IgA)、免疫球蛋白G(IgG)、免疫球蛋白M(IgM)含量的变化情况。【结果】(1)治疗后,2组患者FDI量表、Sunnybrook量表评分均明显改善(P<0.05),且治疗组在改善FDI量表、Sunnybrook量表评分方面明显优于对照组,差异有统计学意义(P<0.05)。(2)治疗后,2组患者WHOQOL-BREF量表评分明显改善(P<0.05);治疗组在改善WHOQOL-BREF量表评分方面优于对照组,但差异无统计学意义(P>0.05)。(3)治疗后,2组患者IgA、IgG、IgM含量均明显改善(P<0.05),且治疗组在改善IgA、IgG、IgM含量方面明显优于对照组,差异有统计学意义(P<0.05)。(4)治疗组总有效率为96.23%(51/53),对照组为81.13%(43/53)。治疗组疗效优于对照组,差异有统计学意义(P<0.05)。【结论】针刺结合穴位埋线治疗周围性面瘫,能明显改善患者面部神经功能及免疫指标IgA、IgG、IgM含量,从而提高患者生活质量,疗效显著。

Objective To explore the effect of acupuncture combined with acupoint catgut embedding on facial nerve and immune indexes in patients with peripheral facial paralysis. Methods One hundred and six patients with peripheral facial paralysis were randomly divided into treatment group and control group,53 cases in each group.Both groups received western medicine combined with electro-acupuncture routine treatment,additionally,the treatment group received acupoint catgut embedding. The treatment lasted 2 continuous months. After 2-month treatment, the changes in facial disability index(FDI)score, Sunnybrook facial nerve grading system score,World Health Organization quality of life(WHOQOL-BREF)score, and the contents of immunoglobulin A(IgA),immunoglobulin G(IgG)and immunoglobulin M(IgM)were observed in the two groups before and after treatment. Results(1)After treatment,the FDI and Sunnybrook scale scores of the two groups were improved(P<0.05),and the improvement in FDI and Sunnybrook scale scores of the treatment group was superior to that of the control group(P < 0.05).(2)After treatment,the WHOQOL-BRE scale scores of the two groups were improved(P<0.05),and the improvement in WHOQOL-BRE scale scores of the treatment group was superior to that of the control group,but the difference being insignificant(P > 0.05).(3)After treatment,the contents of IgA,IgG,IgM of the two groups were improved(P<0.05), and the improvement in contents of IgA, IgG, IgM of the treatment group was superior to that of the control group(P < 0.05).(4)The total clinical response rate in the treatment group was 96.23%(51/53),and that in the control group was 81.13%(43/53),and the clinical efficacy of the treatment group was superior to that of the control group(P < 0.05). Conclusion Acupuncture combined with acupoint catgut embedding is effective for improving facial nerve functions and contents of immune indexes IgA,IgG,IgM in patients with peripheral facial paralysis,thus to promote the patients’ QOL.