人工髋关节置换治疗股骨颈骨折合并尿毒症的疗效及安全性分析

Analysis of the efficacy and safety of hip arthroplasty in treatment of femoral neck fracture combined with uremia

探讨人工髋关节置换手术治疗股骨颈骨折合并尿毒症的临床疗效及安全性。选取2014年1月至2018年12月股骨颈骨折合并尿毒症患者10例作为观察组,随机选取同期股骨颈骨折未合并尿毒症患者20例作为对照组,两组均接受人工关节置换手术治疗。比较两组患者围手术期资料及随访资料。两组患者术前基础疾病、白蛋白相比差异无显著性(P>0.05)。与对照组比较,尿毒症组患者平均年龄更小,术前血红蛋白更低,围手术期输血率更高,入院至手术时间及住院时间更长(P<0.05)。两组患者术后并发症及末次随访髋关节Harris评分比较,差异无显著性(P>0.05)。人工髋关节置换治疗股骨颈骨折合并尿毒症风险高,通过积极的围手术期处理,可以取得较好临床疗效。

To investigate the clinical efficacy and safety of hip arthroplasty in treatment of femoral neck fracture combined with uremia.From January 2014 to December 2018,10 patients with femoral neck fracture combined with uremia were selected as the observation group,and 20 patients with femoral neck fracture without uremia during the same period were selected randomly as the control group.All patients treated by hip arthroplasty surgery.The perioperative data and follow-up data of the two groups were compared.There was no significant difference in preoperative diseases and albumin level between the two groups(P>0.05).The uremia group was younger,had lower preoperative hemoglobin,higher perioperative transfusion rate,longer duration from admission to surgery and hospital stay(P<0.05).There was no significant difference between the two groups in postoperative complications and Hip Harris score at the last postoperative followup(P>0.05).Hip arthroplasty for femoral neck fracture combined with uremia is high risk,good clinical outcome could be achieved through active perioperative management.