上海某社区成人自身免疫性甲状腺疾病患病率及影响因素分析

Analysis of prevalence and influencing factors of adult auto-immune thyroid disease in a community in Shanghai

目的:了解上海某社区成人自身免疫性甲状腺疾病(AITD)患病率及影响因素。方法:采用整群随机抽样的方法抽取上海某社区调查对象381人,其中男性173人,女性208人;平均年龄为(42.62±12.31)岁。收集现场问卷调查、体格检查、实验室检测和影像学检查等数据,分析AITD的患病情况及其影响因素。结果:上海某社区AITD患病率为13.12%,其中男性患病率为8.09%,女性患病率为17.31%,差异有统计学意义(P=0.008)。多因素logistic回归分析结果显示,年龄、BMI、吸烟、饮酒、尿碘水平等影响因素与AITD患病风险未见有统计学意义的相关。结论:AITD是最常见的器官特异性自身免疫性疾病,社区的患病率处于较高水平。

Objective:To explore the prevalence and influencing factors of adult auto-immune thyroid disease(AITD)in a community,Shanghai.Methods:Three hundred and eighty-one people from a community in Shanghai were selected by cluster random sampling,and among them there were 173 men and 208 women;the average age was(42.62±12.31)years old.The data of on-site questionnaire,physical examination,laboratory examination and imaging examination were collected to analyze the prevalence of AITD and its influencing factors.Results:The prevalence rate of AITD in a community in Shanghai was 13.12%,of which the prevalence rate of the males was 8.09%,the prevalence rate of the females was 17.31%,and the difference was statistically significant(P=0.008).Multivariate logistic regression analysis showed that age,BMI,smoking,drinking,urinary iodine level and other factors had no significant correlation with the risk of AITD.Conclusion:AITD is the most common organspecific auto-immune disease,and the prevalence in the community is at a relatively high level.