颈动脉斑块及主动脉瓣钙化与冠心病的相关性

Relationship between carotid plaque combined with aortic valve calcification and coronary heart disease

目的探讨颈动脉斑块及主动脉瓣钙化(AVC)与冠心病的相关性。方法选取滁州市第一人民医院2017年1月至2018年12月收治的疑诊冠心病病人247例,均行冠状动脉造影(CAG)、超声心动图及颈动脉超声检查。根据冠脉造影检查结果分为冠状动脉病变组152例和冠状动脉正常组95例,比较两组颈动脉斑块发生率、主动脉瓣钙化发生率,分析颈动脉斑块及主动脉瓣钙化检查对冠心病的预测价值。结果冠状动脉病变组颈动脉斑块检出率77.6%及主动脉瓣钙化检出率35.5%明显高于冠状动脉正常组32.6%及12.6%(P<0.01);颈动脉斑块与主动脉瓣钙化联合检测对诊断冠心病的特异度为95.8%,阳性预测值是91.8%。结论颈动脉斑块、主动脉瓣钙化与冠心病有显著的相关性,对冠心病有较大的预测价值。

Objective To investigate the relationship between carotid plaque combined with aortic valve calcification and coronary heart disease(CHD).Methods Two hundred and forty-seven inpatients with suspected coronary heart disease underwent coronary angiography(CAG),echocardiography and carotid ultrasound in The First People’s Hospital of Chuzhou form January 2017 to December 2018.According to the results of coronary angiography,patients were assigned into 152 cases of coronary artery disease group and 95 cases of normal coronary artery group.The incidence of carotid plaque and aortic valve calcification were compared between the two groups.The predictive value of carotid plaque and aortic valve calcification examination for coronary heart disease was analyzed.Results The detection rate of carotid plaque(77.6% vs.32.6%)and aortic valve calcification(35.5% vs.12.6%)in coronary heart disease group was significantly higher than that in non-coronary heart disease group(P<0.01).The specificity of combined detection of carotid plaque and aortic valve calcification for the diagnosis of CHD was 95.8%,and the positive predictive value was 91.8%.Conclusion Carotid plaques and aortic valve calcification are significantly correlated with coronary heart disease and have great predictive value for coronary heart disease.