纤维支气管镜吸痰与抗感染联合应用于重症肺部感染患者中的效果

Effect of Combined Bronchoscopy Suction and Anti-infection in Patients with Severe Pulmonary Infection

目的探讨纤维支气管镜吸痰与抗感染联合应用于重症肺部感染患者中的效果。方法选择2018年5月—2019年5月该院收治的重症肺部感染患者94例,以随机数表法将其分为两组,即对照组与研究组各47例。对照组患者采取对症治疗与抗感染治疗,研究组在此基础上应用纤维支气管镜吸痰治疗。对比两组患者的临床疗效、治疗前后炎症因子的变化、恢复情况(体温恢复时间、临床症状消失时间、机械通气时间、血常规恢复时间与住院时间)与不良反应情况。结果研究组治疗的总有效率为95.74%高于对照组78.72%,差异有统计学意义(χ2=6.114,P<0.05)。治疗后研究组TGF-β(84.25±8.60)ng/L与PCT(3.55±0.40)μg/L低于对照组(95.64±10.02)ng/L、(4.89±0.55)μg/L(t=5.914、13.510,P<0.01)。两组治疗期间均未见明显的不良反应。结论纤维支气管镜吸痰与抗感染联合治疗重症肺部感染效果确切,安全性佳。

Objective To explore the effect of combined bronchoscopy suction and anti-infection in patients with severe pulmonary infection.Methods A total of 94 patients with severe pulmonary infection treated in the hospital from May 2018 to May 2019 were selected and divided into two groups by random number table method,that is,47 cases in the control group and the study group each.Patients in the control group were treated symptomatically and anti-infectively,and the research group was treated with fiberoptic bronchoscopy.The clinical efficacy,changes in inflammatory factors before and after treatment,and recovery(temperature recovery time,clinical symptoms disappearance time,mechanical ventilation time,blood routine recovery time and hospitalization time) and adverse reactions were compared between the two groups of patients.Results The total effective rate of treatment in the study group was95.74% higher than that in the control group of 78.72%,and the difference was statistically significant(χ2=6.114,P<0.05).After treatment,the TGF-β(84.25±8.60) ng/L and PCT(3.55±0.40) μg/L in the study group were lower man those in the control group(95.64±10.02) ng/L,(4.89±0.55)μg/L(t=5.914,13.510,P<0.01).No significant adverse reactions were seen during the treatment in both groups.Conclusion The combination of fiberoptic bronchoscopy and anti-infection for the treatment of severe pulmonary infection is effective,safe.