小剂量罗哌卡因复合舒芬太尼在自控硬膜外分娩镇痛中的应用效果

Application effect of low-dose ropivacaine combined with sufentanil in patient-controlled epidural analgesia foRlabor

目的分析小剂量罗哌卡因复合舒芬太尼在自控硬膜外分娩镇痛中的应用效果。方法选取120例产妇,按照入院顺序分为对照组(n=60)与观察组(n=60),对照组采用产科常规处理,观察组采用小剂量罗哌卡因复合舒芬太尼镇痛,比较2组产妇镇痛效果。结果用药前2组产妇视觉模拟评分法(VAS)评分无显著差异(P>0.05);用药后10、60、120 min及宫口全开时,观察组VAS评分显著低于对照组(P<0.05)。观察组各产程时间均显著短于对照组(P<0.05)。观察组新生儿Apgar评分、改良Bromage评分均显著高于对照组(P<0.05);观察组应用缩宫素产妇比率显著低于对照组(P<0.05)2组胎儿窘迫及产后出血发生率无显著差异(P>0.05)。观察组不良事件发生率为5.00%,与对照组不良事件发生率6.67%比较无显著差异(P>0.05)。结论在自控硬膜外分娩镇痛中使用小剂量罗哌卡因复合舒芬太尼可显著改善产妇分娩结局,缓解分娩疼痛,缩短产程时间。

Objective To analyze the effect of low-dose ropivacaine combined with sufentanil in patient-controlled epidural analgesia foRlabor.Methods A total of 120 puerperas were selected and divided into control group(n=60)and observation group(n=60)according to the ordeRof hospital admission.The control group was treated by routine measures,while the observation group was treated with low-dose ropivacaine combined with sufentanil foRanalgesia.Analgesic effects were compared between the two groups.Results Before treatment,there was no significant difference in score of Visual Analogue Scale(VAS)between the two groups(P>0.05).At the time points of 1060,120 minutes afteRtreatment and orifice of uterus fully opening,the scores of VAS in the observation group were significantly loweRthan those in the control group(P<0.05).The time of each birth process in the observation group was significantly shorteRthan that in the control group(P<0.05).The ApgaRscore and the modified Bromage score of the newborns in the observation group were significantly higheRthan those in the control group(P<0.05).The ratio of pregnant women with oxytocin administration in the observation group was significantly loweRthan that in the control group(P<0.05).There were no significant differences in the incidence of fetal distress and postpartum hemorrhage between the two groups(P>0.05).The incidence of adverse events was 5.00%in the observation group,which showed no significant difference when comparing with 6.67%in the control group(P>0.05).Conclusion Application of low-dose ropivacaine combined with sufentanil in patient-controlled epidural analgesia foRlaboRcan significantly improve delivery outcome,relieve laboRpain and shorten the time of laboRprocess.