中医食疗结合常规疗法干预老年高脂血症痰湿内阻证临床研究

Clinical Study on Intervention of Diet therapy of Chinese Medicine Combined with Routine Therapy on Senile Patients with Hyperlipidemia with Phlegm-Dampness Internal Obstruction Syndrome

目的:观察在常规疗法基础上加用中医食疗干预老年高脂血症痰湿内阻证患者的效果。方法:将120例患者随机分为对照组和治疗组各60例。对照组口服辛伐他汀片,并给予改善生活方式措施。观察组在对照组治疗措施的基础上给予中医食疗指导。2组疗程均为12周。干预前后检测2组患者的血脂指标,包括总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)水平,记录体质量、腹围及体质量指数(BMI),评定痰湿内阻证评分。比较2组的疗效。结果:治疗后,治疗组疗效优于对照组(P<0.05)。2组TC、TG、LDL-C水平均较治疗前降低,HDL-C均较治疗前升高,差异均有统计学意义(P<0.05)。治疗组TC、TG、LDL-C水平均低于对照组,HDL-C高于对照组,差异均有统计学意义(P<0.05)。治疗组体质量下降、腹围缩小,与治疗前比较,差异均有统计学意义(P<0.05)。2组痰湿内阻证评分均较治疗前下降(P<0.05)。治疗组痰湿内阻证评分低于对照组(P<0.05)。结论:在常规疗法基础上加用中医食疗干预老年痰湿内阻型高脂血症患者,能进一步控制血脂情况,改善临床症状,减少心血管疾病的风险因素。

Objective:To observe the effect of the intervention of diet therapy of Chinese medicine on senile patients with hyperlipidemia with phlegm-dampness internal obstruction syndrome based on routine therapy.Methods:A total of 120 cases of patients were randomly divided into the control group and the treatment group,60 cases in each group.The control group was given oral administration of simvastatin tablets and measures to improve lifestyle.The observation group was additionally given guidance of diet therapy based on the treatment of the control group.Both groups were treated for 12 weeks.Before and after intervention,the levels of blood lipids including total cholesterol(TC),triglyceride(TG),low-density lipoprotein cholesterol(LDL-C)and high-density lipoprotein cholesterol(HDL-C)in the two groups were detected;the body weight,abdominal circumference and body mass index(BMI)were recorded;the scores of phlegm-dampness internal obstruction syndrome were evaluated.The curative effect was compared between the two groups.Results:After treatment,the curative effect in the treatment group was better than that in the control group(P<0.05).The levels of TC,TG and LDL-C in the two groups were decreased when compared with those before treatment,and the levels of HDL-C were increased,differences being significant(P<0.05).The levels of TC,TG and LDL-C in the treatment group were lower than those in the control group,and the level of HDL-C was higher,differences being significant(P<0.05).The body weight and abdominal circumference in the treatment group were decreased when compared with those before treatment,differences being significant(P<0.05).The scores of phlegm-dampness internal obstruction syndrome in the two groups were decreased when compared with those before treatment(P<0.05),and the score in the treatment group was lower than that in the control group(P<0.05).Conclusion:The diet therapy of Chinese medicine based on routine therapy in intervening senile patients with hyperlipidemia with phlegm-dampness internal obstruction syndrome can further control blood lipids,improve clinical symptoms and reduce the risk factors of cardiovascular diseases.