摘要
《中国药典》2015年版采用3组不同色谱分析条件分别对明目地黄丸中的马钱苷、芍药苷和丹皮酚的含量进行测定,该方法操作复杂,且费时.因此,为简化明目地黄丸中有效成分的测定方法,对《中国药典》中该中成药的高效液相色谱法的色谱条件进行优化,改变波长程序和改进供试品制备方法,实现了仅用1组色谱系统就可同时测定明目地黄丸中马钱苷、芍药苷、丹皮酚的含量,且该方法操作简便、快捷、准确度高.
The contents of loganin,paeoniflorin and paeonol in Mingmu Dihuang Pills were determined by three different chromatographic analysis conditions in Chinese Pharmacopoeia 2015.The method was complex and time-consuming.Therefore,in order to simplify the determination method of the effective components in Mingmu Dihuang Pills,the chromatographic conditions of the traditional Chinese medicine in the Chinese Pharmacopoeia were optimized,and the wavelength program was changed.Meanwhile,the preparation method of the sample was improved,so as to realize the simultaneous determination of loganin and paeoniflorin and paeonol in Mingmu Dihuang Pills with only one set of chromatographic systems.The improved method is simple,fast and accurate.
作者
禄美云
LU Meiyun(Drug Inspection Center,Kunming Food and Drug Inspection Research Institute,Kunming,Yunnan,China 650100)
出处
《昆明学院学报》
2020年第3期99-104,共6页
Journal of Kunming University
