维生素E的“前世”和“今生”

The past and present of vitamin E

维生素E作为人和动物体必需且最主要的抗氧化剂之一,功效广泛,可用作维持机体正常功能,提高机体生育能力、免疫能力等,在医药、饲料等领域中占有重要地位。维生素E是我国的民生基础产业产品,也是国际市场上用途非常广泛、产销量极大的三大维生素支柱产品之一,市场前景广阔。自1938年维生素E被成功合成以来,维生素E的合成技术经历了80多年的历史,随着技术的发展逐渐形成了目前比较稳定的市场格局。本文总结了维生素E合成技术一路的发展,主要包括天然提取、化学全合成、生物全合成,以及生物-化学合成等,着重介绍了主流的化学全合成技术,以及新兴产业技术——合成生物技术引领的生物-化学合成技术。回顾了维生素E的发展历史并对未来发展进行了展望。

Vitamin E,as one of the most important antioxidants in biological systems,has a variety of biological functions.For example,it can maintain normal metabolism and improve the fertility and immunity of humans and animals.It occupies an important position in the fields of medicine and feed.It is a basic supplemental product for people in China and also one of the three major vitamin products with big production volume and sale in the international market.Since it was developed in 1938,the synthesis technology of vitamin E has experienced a history of more than 80 years.With technological innovations,a relatively stable market has gradually formed for vitamin E.Here,we summarized the development of vitamin E synthesis technology,including extraction from natural resources and synthesis with chemical,biological and biochemical routes.The technologies of chemical and biochemical synthesis as the most competitive processes are introduced in details.The history of vitamin E is reviewed and the future development of vitamin E is prospected.