曼月乐和醋酸甲羟孕酮在围绝经期异常子宫出血治疗中的应用

Application of Mirena and Medroxyprogesterone Acetate in the Treatment of Perimenopausal Abnormal Uterine Bleeding

目的:探究曼月乐和醋酸甲羟孕酮在围绝经期异常子宫出血治疗中的应用。方法:择取2018年1月~2019年11月期间某院妇科门诊诊治的围绝经期异常子宫出血诊断性刮宫术后围绝经期异常子宫出血患者共100例,按照随机数字表法进行分组,包括上曼月乐宫内节育器组(n=45)和口服醋酸甲羟孕酮组(n=55),比较两组患者月经情况、子宫内膜厚度、临床治疗有效率。结果:治疗后曼月乐组患者月经量、月经时间少于甲羟孕酮组,子宫内膜厚度低于甲羟孕酮组,临床治疗总有效率高于甲羟孕酮组(P<0.05)。结论:围绝经期异常子宫出血患者开展曼月乐治疗效果理想,降低子宫内膜厚度、复发率,值得推广。

Objective:To explore the application of Mirena and medroxyprogesterone acetate in the treatment of perimenopausal abnormal uterine bleeding.Methods:A total of 100 patients with perimenopausal abnormal uterine bleeding diagnosed and treated in the gynecological clinic of a hospital from January 2018 to November 2019 were selected and divided into two groups according to the random number table method,including Mirena intrauterine device(n=45)and oral medroxyprogesterone acetate(n=55).Menstrual condition,endometrial thickness,and clinical treatment efficiency were compared between the two groups.Results:After treatment,the menstrual volume and menstrual time of the patients in the Mirena group were less than those in the mehydroxyprogesterone group,the endometrial thickness was lower than that in the mehydroxyprogesterone group,and the total effective rate of clinical treatment was higher than that in the mehydroxyprogesterone group(P<0.05).Conclusion:Mirena treatment is effective in patients with abnormal uterine bleeding during perimenopausal period,and it can reduce the endometrial thickness and recurrence rate,which is worthy of promotion.